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Post by Admin on Mar 16, 2018 4:46:00 GMT
My take on Domoic Acid: I do not believe State Agency scientists fully understand the relationship between Marie Toxins and the human body!!! The consequences of failing to achieve an understanding between all the factors are extreme. Those that think they do are playing Russian Roulette. Consider there is a huge difference between accelerating levels of contamination that spikes upward and decelerating levels of the diatom that is responsible for Domoic acid. Considering the complex factors of contamination of marine organisms we recommend harvesting those marine organisms when the level of contamination is zero. My friends, Just a note to inform you that the State is allowing the sale of crabs when the level of Domoic acid exceeds the threshold limit to issue an alert that would normally prohibit the sale of crabs infected. Their rational is that the crabs are safe for consumption if the crab butter is removed from the crabs prior to cooking and marketing them as Crab Clusters.
I do not have to tell you that this a bad Idea for any number of reasons. The most glaring in that it diminishes just how toxic Domoic acid actually is when compared to the closing of other marine species, such as razor clams.
Frankly, the contamination of our clams, oysters and crabs products is completely out of control. The threat to our Coastal Economy is real. Inadequate sewage processing facilities in conjunction with allowing pollution of Oregon's State waters by storm water runoff are the source of the problems.
Bill Lackner for the members of the Clam Diggers Association of Oregon.
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Post by Admin on Nov 2, 2018 17:43:36 GMT
The CDAO recommends caution when considering the decision to consume shellfish contaminated with marine toxins. We recommend against harvesting shellfish or crabs during periods when the toxic levels of marine toxins are rising. We recommend consuming shellfish and crab only when the level of contamination is ZERO!!!
The rewards of consuming contaminated shellfish or crabs ARE NOT worth the risk. Children and the elderly are at risk when exposed to any level of Domoic Acid or PSP. Click on the following link to view the complete text of the entire study.
Domoic Acid Toxicologic Pathology: A Review
Olga M. Pulido1,2
Abstract
Domoic acid was identified as the toxin responsible for an outbreak of human poisoning that occurred in Canada in 1987 following consumption of contaminated blue mussels [Mytilus edulis]. The poisoning was characterized by a constellation of clinical symptoms and signs. Among the most prominent features described was memory impairment which led to the name Amnesic Shellfish Poisoning [ASP]. Domoic acid is produced by certain marine organisms, such as the red alga Chondria armata and planktonic diatom of the genus Pseudo-nitzschia. Since 1987, monitoring programs have been successful in preventing other human incidents of ASP. However, there are documented cases of domoic acid intoxication in wild animals and outbreaks of coastal water contamination in many regions world-wide. Hence domoic acid continues to pose a global risk to the health and safety of humans and wildlife. Several mechanisms have been implicated as mediators for the effects of domoic acid. Of particular importance is the role played by glutamate receptors as mediators of excitatory neurotransmission and the demonstration of a wide distribution of these receptors outside the central nervous system, prompting the attention to other tissues as potential target sites. The aim of this document is to provide a comprehensive review of ASP, DOM induced pathology including ultrastructural changes associated to subchronic oral exposure, and discussion of key proposed mechanisms of cell/tissue injury involved in DOM induced brain pathology and considerations relevant to food safety and human health.
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Post by south on Nov 2, 2018 21:14:33 GMT
Crab Commission and their agenda:
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Post by south on Nov 2, 2018 21:19:39 GMT
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Post by south on Nov 2, 2018 21:21:59 GMT
How come sports are not invited?
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Post by south on Nov 3, 2018 16:24:10 GMT
Oregon Outdoor Sports Commission
Hey Bill maybe its time !
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Post by Admin on Nov 3, 2018 18:31:45 GMT
South: All commissioners should be elected!!!
Appointing commissioners invites corruption and issue bias.
Their reaction to the discharge of 2.1 million gallons of raw sewage into Siletz Bay says it all!
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Post by south on Nov 3, 2018 18:41:47 GMT
Merging the Sports group into one group, aka: clam diggers, crabbers, berry pickers, mushroom pickers, fisherman, hunters. Elect the leaders who promote healthy subsistence lifestyle for all Oregonians and future Oregonians. We fail because we are not organized.
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Post by Admin on Nov 3, 2018 21:04:40 GMT
The ODFW Commission meets in secret session on Nov 6th. in an effort to censor the public's objections to their actions.
Friday, November 2, 2018
SALEM, Ore.—The Oregon Fish and Wildlife Commission will meet by conference call at 2 p.m. on Tuesday, Nov. 6. See the meeting agenda at www.dfw.state.or.us/agency/commission/minutes/18/11_nov/110618.asp
The Commission will meet in open public session to ratify temporary rules implemented by the Department and then will go into a closed Executive Session to consult with legal counsel with respect to litigation filed or likely to be filed against the Commission. Department staff will host the meeting. Members of the public interested in listening to the public session may listen in at ODFW Headquarters, 4034 Fairview Industrial Drive SE, Salem.
The closed Executive Session is being held pursuant to ORS 192.660(2)(h). Members of the media can attend but may not report on proceedings during the Executive Session. Members of the media wishing to attend the Executive Session can do so at ODFW Headquarters, 4034 Fairview Industrial Drive SE, Salem.
###
Contact:
Michelle Dennehy, (503) 947-6022, Michelle.N.Dennehy@state.or.us
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Post by Admin on Dec 8, 2018 19:10:38 GMT
California sea lions exposed to a toxin in algae develop a form of epilepsy that is similar to one in humans, according to a new study led by Stanford University School of Medicine researchers.
Every year, hundreds of sea lions wash up along the California coast, suffering seizures caused by exposure to domoic acid, a neurotoxin that can produce memory loss, tremors, convulsions and death. Domoic acid is produced by algae blooms that have been proliferating along the coast in recent years, accumulating in anchovies and other small fish that the sea lions feed on, said Paul Buckmaster, PhD, DVM, professor of comparative medicine at Stanford.
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Post by Admin on Dec 8, 2018 20:57:29 GMT
Characterization of Renal Toxicity in Mice Administered the Marine Biotoxin Domoic Acid
Jason A. Funk,* Michael G. Janech,* Joshua C. Dillon,* John J. Bissler,† Brian J. Siroky,† and P. Darwin Bell*‡
*Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina; †Division of Nephrology and Hypertension, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio; and ‡Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina
ABSTRACT
Domoic acid (DA), an excitatory amino acid produced by diatoms belonging to the genus Pseudo-nitzschia, is a glutamate analog responsible for the neurologic condition referred to as amnesic shellfish poisoning. To date, the renal effects of DA have been underappreciated, although renal filtration is the primary route of systemic elimination and the kidney expresses ionotropic glutamate receptors. To characterize the renal effects of DA, we administered either a neurotoxic dose of DA or doses below the recognized limit of toxicity to adult Sv128/Black Swiss mice. DA preferentially accumulated in the kidney and elicited marked renal vascular and tubular damage consistent with acute tubular necrosis, apoptosis, and renal tubular cell desquamation, with toxic vacuolization and mitochondrial swelling as hallmarks of the cellular damage. Doses$0.1 mg/kg DA elevated the renal injury biomarkers kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin, and doses$0.005 mg/kg induced the early response genes c-fos and junb. Coadministration of DA with the broad spectrum excitatory amino acid antagonist kynurenic acid inhibited induction of c-fos, junb, and neutrophil gelatinase-associated lipocalin. These findings suggest that the kidney may be susceptible to excitotoxic agonists, and renal effects should be considered when examining glutamate receptor activation. Additionally, these results indicate that DA is a potent nephrotoxicant, and potential renal toxicity may require consideration when determining safe levels for human exposure.
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